Op-brai140011 1..2
نویسندگان
چکیده
1 Johns Hopkins School of Medicine, 1830 Monument Street, Suite 2-300, Baltimore, Maryland, 21205, USA 2 John van Geest Centre for Brain Repair, University of Cambridge, E.D. Adrian Building, Forvie Site, Robinson Way, Cambridge, UK 3 Section of Retinal Ganglion Cell Biology, Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institutes of Health, 6 Center Drive, MSC 0606, Building 6, Room 212, Bethesda, Maryland, USA
منابع مشابه
Opposite Categories and Contravariant Functors
The opposite category of a category, contravariant functors and duality functors are defined. Next we state the proposition (1) the objects of C, the morphisms of C, the cod-map of C, the dom-map of C, (the composition of C),the id-map of C is a category. Let us consider C. The functor C op yielding a strict category is defined by the condition (Def. 1). (Def. 1) C op = the objects of C, the mo...
متن کاملSpleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice.
Osteoclasts are generated from monocyte/macrophage-lineage precursors in response to colony-stimulating factor 1 (CSF-1) and receptor activator of nuclear factor-κB ligand (RANKL). CSF-1-mutated CSF-1(op/op) mice as well as RANKL(-/-) mice exhibit osteopetrosis (OP) caused by osteoclast deficiency. We previously identified RANKL receptor (RANK)/CSF-1 receptor (CSF-1R) double-positive cells as o...
متن کاملAdenoidectomy May Not Be Effective to Reduce the Number of Hospital Visits for Sinusitis
BACKGROUND The objective of this study was to compare post-operative (post-op) visits for sinusitis between adenoidectomy and non-adenoidectomy participants (control). METHODS Using the national cohort study from the Korean Health Insurance Review and Assessment Service, we used 1:4 matching to select 2,593 adenoidectomy participants and 10,372 control participants. Post-op visits for sinusit...
متن کاملBMP-2 and OP-1 exert direct and opposite effects on renal branching morphogenesis.
The bone morphogenetic proteins, BMP-2 and OP-1, are candidates for growth factors that control renal branching morphogenesis. We examined their effects in embryonic kidney explants and in the mIMCD-3 cell model of collecting duct morphogenesis (mIMCD-3 cells are derived from the terminal inner medullary collecting duct of the SV40 mouse). Osteogenic protein-1 (OP-1), at a dose of 0.25 nM, incr...
متن کاملEnforced Expression of Bcl-2 in Monocytes Rescues Macrophages and Partially Reverses Osteopetrosis in op/op Mice
Osteopetrotic (op/op) mice lack functional M-CSF and have depressed levels of macrophages and osteoclasts. We prepared transgenic mice (hMRP8bcl-2) that express human Bcl-2 in monocytes. In vitro hMRP8bcl-2 monocytes do not undergo apoptosis in the absence of serum and M-CSF, while op/op and wild-type monocytes die. These Bcl-2-expressing monocytes spontaneously undergo macrophage differentiati...
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